Pipeline

Neurological disorders are diseases of the central and peripheral nervous system including neurodegenerative disorders such as Alzheimer‘s disease and related dementias, Parkinson’s disease, ALS, Huntington‘s disease, multiple sclerosis, but also traumatic and/or cerebrovascular diseases like stroke, brain tumors and Spinal Cord Injury.

 

These disorders are of major clinical problems,

currently with no satisfactory treatment available.

OUR PRODUCTS

Our candidates, close to start clinical development, meet criteria being highly desirable features for CNS damage treatment

  • Our products are small peptides derived from the most conserved sequence of the thrombospondin repeat (TSRs) of the SCO-spondin, a naturally secreted protein with potent activity during neurogenesis
  • TSRs are active domains involved in various context-dependent pathways and contributing in angiogenesis and axon guidance

     

 

  • Our drug candidates have multifunctional activities on neural cells, encompassing:

    • Neuroprotection with strong anti-oxidative properties & anti-apoptotic activities
    • Regenerative & remodeling properties including neurite outgrowth to restore lost function
    • Cellular plasticity mechanisms