Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ- Spondin-Derived Peptide: A Randomized, Placebo- Controlled, Double-Blind, Single Ascending Dose Firstin- Human Study

ORIGINAL RESEARCH article

Neurology and Therapy, 2022 – July, Vol.11.

Valérie Bourdès¹ . Peter Dogterom² . André Aleman³ . Pierre Parmantier⁴ . Damien Colas⁴ . Sighild Lemarchant¹ . Sébastien Marie¹ . Thomas Chou⁵ . Khalid Abd-Elaziz² . Yann Godfrin^{1, 6}

1. Axoltis Pharma, 60 Avenue Rockefeller, 69008 Lyon, France
2. QPS Netherlands B.V., Groningen, The Netherlands
3. Department of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
4. Athena Bio Consulting, Lyon, France
5. QPS LLC, Newark, DE, USA
6. Godfrin Life Sciences, 8 impasse de la source, 69300 Caluire-et-Cuire, France